What we do
We exist to advance medical research, improve human health and change people’s lives. You can help us do it.
Mental health
A Medical Research Foundation-MRC funded study to explore the use of new behavioural techniques to help treat binge eating disorder, focusing on ‘re-writing’ reward memories.
Binge eating disorder (BED) is a condition in which the ability to resist food - or to stop eating once an episode of overeating has begun - is impaired. BED is the most prevalent eating disorder and typically begins in adolescence. However, it is a chronic problem, lasting for many years after onset and contributing to a variety of serious psychiatric and metabolic health problems.
While BED has received relatively little attention from neuroscientific researchers, there are striking parallels between BED and substance use disorders, which also typically develop in adolescence and have been the subject of extensive research. This has shown that maladaptive reward memories are present in drug addiction. Given the overlap in the behaviours, symptoms, age of onset and comorbidity between drug addiction and BED, these reward memories also likely play a key role in BED.
Dr Sunjeev Kamboj has been awarded a Medical Research Foundation-MRC research grant to explore the use of new behavioural techniques to help treat BED, focusing on ‘re-writing’ maladaptive reward memories. The findings from this study could in future support people seeking help for BED.
Eating disorders are life-threatening mental illnesses that can start in adolescence and affect 15 per cent of young women and up to four per cent of young men. The number of people being diagnosed and entering in-patient treatment for eating disorders in England alone has increased at an average rate of 7% per annum since 2009. Eating disorders are complex and we are yet to understand why someone develops one or how best to treat them. A whole range of different factors influence the development of eating disorders including genetics, psychological, environmental, social and biological factors. We need a better understanding of the causes of eating disorders and jointly with the Medical Research Council we have funded research to develop this understanding.
We fund and support the most promising health research wherever we discover great opportunities that are not being pursued. We use our donations responsibly and ensure we make the greatest impact where it is most needed.
DONATE